Utilising CAPTURE-XT®, a rapid pathogen concentration and sample clean-up technology, as a front-end for Next-Generation Sequencing of Mycobacterium tuberculosis from clinical sputum samples

The aim of this project was to explore the application of CAPTURE-XT®, a microfluidic lab-on-chip pathogen concentration system which utilizes dielectrophoresis to selectively capture and concentrate whole MTB cells from sputum, as a potential front-end for NGS.